StemBeads®

Coupling innovation with meaningful scientific benefit by optimizing reagents for improved cell growth.

What are StemBeads?

StemBeads are a revolutionary controlled-release growth factor technology. The StemBeads product is currently used for improved cell culture in more than 100 scientific laboratories globally. 

Sustained Release Protein Cell Culture

Many growth factors have extremely short half-lives in culture (some as short as 45 minutes!), so maintaining a positive growing environment is very difficult. The short half-life causes variability in growth factor levels, a need for daily feeding, and low-quality cell growth.

To solve these problems, we developed a way to control the release of proteins with biocompatible StemBeads.

StemBeads technology encapsulates a growth factor in a PLGA hydrogel that stabilizes the protein and releases it steadily over several days. With growth factor levels stabilized, spontaneous differentiation is reduced, pluripotency is increased, and feeding schedules are reduced to only 2-3 times per week.

StemBeads are added to your medium to achieve a desired growth factor release, sustained over several days. Following, the beads are washed from the culture, the medium is replaced, and the process repeated as required.

Several Different Growth Factors 

StemCultures currently offers StemBeads for several different growth factors (check our entire StemBeads listing here). The most common applications of our products are for human pluripotent stem cell cultures, but any cell line dependent on these growth factors can benefit from StemBeads. We also produce custom beads to fit your specific needs.

Learn more about StemBeads® products and how they can serve you through this animated informational video. For more information about the product, visit our shop page or contact us.

Now Featuring Qkine High Purity Growth Factors

Qkine high purity animal-origin free growth factors are now available in StemCultures micro-encapsulation, StemBeads technology for controlled-release.

StemCultures technology increases protein stability, with Qkine high purity, bioactive growth factors and cytokines, these products dramatically improve the reproducibility and scalability of cell cultures. 

Shop the entire line of StemBeads Qkine here